1. Perinatal transmission of hepatitis B virus (HBV) was lower in mothers treated with tenofovir disoproxil fumarate (TDF) compared to controls. 2. No significant difference in rates of birth defects found between infants of mothers receiving TDF compared to no TDF. Evidence Rating Level: 1 (Excellent) Study Rundown: Serious consequences of chronic HBV infection include cirrhosis
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