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Parental hopes for critically ill children are dynamic

1. The most commonly reported parental hopes for critically ill children fell within the domains of quality of life, concerns regarding physical body, future well-being, and length of life. 2. Over a...

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Quadrivalent recombinant influenza vaccine noninferior to inactivated vaccine

1. The quadrivalent recombinant influenza vaccine (RIV4) was noninferior when compared with the quadrivalent inactivated influenza vaccine (IIV4) for immunogenicity. Evidence Rating Level: 1...

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Prevalence of cerebral palsy in preterm infants changes over time

1. In preterm infants followed over a 3.75-year study period, the overall prevalence of cerebral palsy (CP) decreased from 16% to 12%, the prevalence of severe CP decreased from 26% to 16%, but the...

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Emotional regulation intervention linked to decreased high risk sexual behavior

1. Adolescents with no baseline sexual activity who underwent an emotional regulation (ER) sexual health intervention were less likely to report first-time vaginal or anal sex over a follow-up period...

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Safety confirmation of propranolol use in treatment of infantile hemangiomas

1. In healthy infants, there was no significantly increased risk for cardiovascular or metabolic events associated with propranolol use for treatment of infantile hemangioma. However, there was an...

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Wide international variation in survival for periviable neonates

1. Survival of neonates born at 22 weeks’ gestation ranged from 1.8 to 22.3% using all live births as the denominator, and this variation declined when incorporating births categorized as stillborn or...

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Neonatal neuroimaging with strong negative predictive value for developmental...

1. In multivariate analyses, adverse late cranial ultrasound findings (CUS) were an independent risk factor for full scale IQ scores <70 (FSIQ <70). Adverse late cranial ultrasound findings and...

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Lowering public insurance income limits shifts costs to families and hospitals

1. Simulations that lowered the public insurance eligibility to 300%, 200% and 100% of the federal poverty line (FPL) resulted in a sizeable and increasing number of theoretically uncovered...

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Extreme preterm birth linked to hypertension at school age

1. Within a cohort of infants born extremely preterm (EPT), there were elevated rates of high systolic blood pressure (SBP≥90%ile) and hypertension (SBP≥95%ile) when these children reached school age....

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Risk of autism in offspring linked to maternal pregestational diabetes and...

1. Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a child with a...

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Longitudinal BMI growth curves for preterm infants internally validated

Body mass index (BMI) growth curves generated with longitudinal data for preterm infants demonstrated an initial decline in BMI driven by weight, followed by a linear increase in weight that was more...

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Prenatal and postnatal homelessness linked with poorer health outcomes

1. Children <4 years of age with a history of prenatal or postnatal homelessness were more likely to have prior hospitalizations, fair or poor health status and developmental risk compared to...

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Palliative care consultation linked to lower deaths by failed code resuscitation

1. Among deaths at one, large children’s hospital, the most common mode of inpatient death was withdrawal of life sustaining technologies, followed by nonescalation of care during or at the time of...

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Large proportion of late preterm infants and older admitted to the NICU

1. Infants ≥ 34 weeks’ gestational age (GA) comprised 75% of the median proportions of neonatal intensive care unit (NICU) admissions across level II-IV NICUs, and only 15% of this group were...

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Recurrence of Group B Streptococcal infection similar in shortened and...

The rates of Group B Streptococcal (GBS) bacteremia recurrence in infants with an initial course of late-onset infection who received shortened and prolonged IV antibiotic therapy were 1.8% and 2.3%,...

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Preterm birth associated with lower high school academic performance

1. In this retrospective cohort study, birth at earlier gestational age (GA) was associated with worse survival rates and increased hospitalization rates in the first 10 years of life, with respiratory...

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Rates of neurodevelopmental impairment unchanged in infants born ≤500g in Japan

The rate of neurodevelopmental impairment (NDI) in infants born ≤500g in Japan between 2003-2012 was 59%, and the prevalence of NDI did not significantly change over the 10-year period. Evidence Rating...

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Parents of children with autism report greater difficulty accessing health care

1. The prevalence of autism spectrum disorder (ASD) through the National Survey of Children’s Health (NSCH) was estimated to be 2.5% in children 3-17 years of age. Parents of children with ASD were...

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Study finds that pediatric residents rarely perform neonatal intubation

1. Advance practitioners and neonatal fellows had the highest rates of neonatal tracheal intubation (TI) attempts in the neonatal intensive care unit (NICU) and delivery room (DR), while residents had...

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Significant unreimbursed costs linked to care coordination for medically...

The estimated nonreimbursed staff costs of care coordination for medically complex children was conservatively estimated to be 145-210% per child per month. Evidence Rating: Level 4 (Below Average)...

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